Data Mining for Systematic Reviews and Meta-Analyses in Health Sciences

The work carried out in this WP involves R&D activities in the field of evidence-based medicine, including topics such as systematic reviews and meta-analyses in several fields of health sciences, through data mining of biomedical literature and databases. The work will be carried out in close collaboration with the Mathematics and Medical Sciences departments at UBI, and associated health institutions.

Team & Collaborators

• Luísa Pereira | WP leader
• Assunção Vaz Patto
• Luís Taborda Barata
• Ângelo Luís
• Francisca Mendonça | Grantee, C4-UBI (05/2019-02/2020)
• Adalberto Fernandes dos Santos | Grantee, C4-UBI

Patents

• Luís, Â., Pereira, L., Domingues, F., & Ramos, A. (2020). Filme funcional à base de carboximetil xilanas com incorporação de óleo essencial de alcaçuz e suas propriedades antioxidantes, antibacterianas e antibiofilme. Patent request BBCA/1A, n. 115034.

Publications

Journal articles

• Mateus, C, Martins, R., Luís, Â., Oleastro, M., Domingues, F., Pereira, L., Ferreira, S. (2021). Prevalence of Arcobacter: from farm to retail – A systematic review and meta-analysis. Food Control, 128,  (***)
• Faias, S., Cravo, M., Chaves, P., Pereira, L. (2021). A comparative analysis of glucose and CEA in Diagnosis of Pancreatic Mucinous Cysts: A Systematic Review and Meta-analysis, Gastrointestinal Endoscopy, 94(2), 235. (***)
• Feijó, M., Martins, R., Socorro, S., Pereira, L., Correia, S. (2021). Exposure to the endocrine disrupting chemical vinclozolin and male reproductive outcomes in rodents: a systematic review and meta-analysis, Biology of Reproduction, 104(5), 962.
• Amaral, L., Luis, Â., Gallardo, E., Domingues, F., Pereira, L. (2020). COVID-19 in children: a systematic review and meta-analysis. Research trends: Current Topics in Virology, 17, 1-49.
• Vargas, A., Luís, Â., Barroso, M., Gallardo, E., Pereira, L. (2020). Psilocybin as a new approach to treat depression and anxiety: a systematic review and meta-analysis of clinical trials. Biomedicines, 8 (9), 331.
• Luís, Â., Marcelino, H., Rosa, C., Domingues, F., Pereira, L., Cascalheira, J.F. (2020). The effects of cannabinoids on glioblastoma growth: a systematic review with meta-analysis of animal model studies. European Journal of Pharmacology, 876, 173055.
• Almeida, M., Soares, M., Ramalhinho, A., Moutinho, J.F., Breitenfeld, L., Pereira, L. (2020). The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis. Breast Cancer Research and Treatment, 179, 523-532.

(***) Articles published in a top 10% most cited journal of the respective field.

Posters in Conferences

• Luís, H. Marcelino; C. Rosa; F. Domingues; L. Pereira; J. Cascalheira (2020) “The effects of cannabinoids on glioblastoma: results from a meta-analysis of animal model studies”. Webinar Cancer Biology: From Basic to Translational Research – September 2020 (Best poster award).
• Almeida, M. Soares, A. Ramalhinho, J. Moutinho, L. Breitenfeld, L. Pereira (2019) “The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis”. COGI 27th World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI) COGI Paris, France – November 2019.

Educational articles for general audience

• A. Luís (2020) “Psilocybin”, Scholarly Community Encyclopedia (Subjects: Psychiatry)

Courses

• Luísa Pereira was a trainer at the IPO Training Center, in the course “Research Methodology”, Module I – “State of art. Systematic reviews and meta-analysis” (May 9, 2019).
• Assunção Vaz Patto, Luís Taborda Barata, Luísa Pereira, Jorge Gama Ângelo Luís and Ramiro Pastorinho taught a course on systematic reviews with meta-analysis for PhD students at FCS (1st edition: November 2020; 2nd edition: November 2021)

Related publications

• Luís, Â.,  Domingues, F., & Pereira, L. (2019) The anti-obesity potential of Ilex paraguariensis: results from a meta-analysis. In Brazilian Journal of Pharmaceutical Sciences, vol.55, e17615.
• Laia-Dias, I., Lozoya-Ibáñez, C., Skypala, I., Gama, J.M.R., Nurmatov, U., Lourenço, O., & Taborda-Barata, L. (2019) Prevalence and risk factors for food allergy in older people: protocol for a systematic review. In BMJ Open, 9(8).
• Faias, S., Pereira, L., Luís, Â., Cravo, M., Pereira, A. D., & Torres, J. (2019). KRAS in Cyst Fluid Obtained by EUS-FNA in Pancreatic Cystic Lesions: A Systematic Review and Meta-analysis. In Pancreas, 48(6), 749-758.
• Faias, S., Pereira, L., Luis, Â., Chaves, P., & Cravo, M. (2019) Genetic testing vs microforceps biopsy in pancreatic cysts: Systematic review and meta-analysis. In World Journal of Gastroenterology, 25(26):3450-3467.
• Ferreira, S., Luís, Â., Oleastro, M., Pereira, L., & Domingues, F. (2019). A meta-analytic perspective on Arcobacter spp. antibiotic resistance. In Journal of Global Antimicrobial Resistance, 16, 130-139.
• Luís, A., Domingues, F., & Pereira, L. (2018). Metabolic changes after licorice consumption: a systematic review with meta-analysis and trial sequential analysis of clinical trials. In Phytomedicine, 39, 17-24.
• Luís, A., Domingues, F., & Pereira, L. (2018). Association between berries intake and cardiovascular diseases risk factors: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials. In Food & Function, 2018, 9, 740-757.
• Luís, A., Domingues, F., & Pereira, L. (2018) Effects of red clover on perimenopausal and postmenopausal women’s blood lipid profile: A meta-analysis. In Climacteric, 21:5, 446-453.
• Luís, A., Domingues, F., & Pereira, L. (2017) Can cranberries contribute to reduce the incidence of urinary tract infections? – A systematic review with meta-analysis and trial sequential analysis of clinical trials. In Journal of Urology, 198(3), 614-621.
• Cruz-Ferreira, A., Cruz-Ferreira, E., Santiago, L., & Taborda-Barata, L. (2017) Epidemiology of injuries in senior male rugby union sevens: a systematic review. In Physician and Sports Medicine, 45(1), 41-48.