Omics data analysis
The work carried out in this WP involves R&D activities in the field of health sciences in close collaboration with CICS-UBI, including multi-disciplinary projects addressing omics data, including genomics, transcriptomics, proteomics and metabolomics.
Team & Collaborators
- Manuel C. Lemos | WP leader
- Catarina I. Gonçalves
- Cecília Santos
- Cândida Tomaz
- Ignacio Verde
- Emanuel Maldonado | PostDoc, UBI (03/2020-02/2022)
- Joana T. Almeida | Research fellow, UBI (04/2019-03/2021)
Publications
Journal articles
- Gonçalves C., Carriço J., Bastos M., Lemos M.. (2022). Disorder of Sex Development Due to 17-Beta-Hydroxysteroid Dehydrogenase Type 3 Deficiency: A Case Report and Review of 70 Different HSD17B3 Mutations Reported in 239 Patients. Int J Mol Sci. 2022, 23(17), 10026.
- Almeida J., Rodrigues D., Guimarães J., Lemos M.. (2020). Vitamin D Pathway Genetic Variation and Type 1 Diabetes: A Case–Control Association Study. Genes, 2020; 11(8):897.
- Alvelos M., Gonçalves C., Coutinho E., Almeida J., Bastos M., Sampaio M., Melo M., Martins S., Dinis I., Mirante A., Gomes L., Saraiva J., Pereira B., Gama-de-Sousa S., Moreno C., Guelho D., Martins D., Baptista C., Barros L., Ventura M., Gomes M., Lemos M.. (2020). Maturity-Onset Diabetes of the Young (MODY) in Portugal: Novel GCK, HNFA1 and HNFA4 Mutations. J Clin Med, 2020 Jan 20;9(1). pii: E288.
Related publications
- Bonifácio M., Mateus C., Alves A., Maldonado E., Duarte A., Domingues F., Oleastro M., Ferreira S.. (2021). Natural Transformation as a Mechanism of Horizontal Gene Transfer in Aliarcobacter butzleri. Pathogens 2021, 10, 909.
Related activities
- Project ExoCloud: Cloud prototype for the sequencing and bioinformatics analyzes of the human genome for the diagnostic of hereditary forms of diabetes mellitus, project reference CENTRO-01-0145-FEDER-181249. PI – Professor Manuel C. Lemos (elaborated by Dr. Emanuel Maldonado and Dr. Hugo Torres Vieira).
- Project Next generation sequencing for the diagnosis of children with MODY type diabetes, by Joana T. Almeida, Emanuel Maldonado, Catarina I. Gonçalves and Manuel C. Lemos – awarded with Endocrinology Grant, Dr. Maria da Conceição Barbas, 2020.
- Support to two projects Type 1 diabetes and vitamin D: a genetic association study and Monogenic diabetes: from the clinic to the understanding of the pathogenesis.